人 TFEC (NM_001244583) cDNA克隆

Accession: NM_001244583
基因名称: TFEC
基因别名: TCFEC; TFE-C; TFECL; TFEC-L; bHLHe34; hTFEC-L
基因描述: Homo sapiens transcription factor EC (TFEC), transcript variant 3, mRNA.
种属: Human
CDS区长度: 843 (查看编码区序列)
翻译后氨基酸长度: 280 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (c) is shorter and has a distinct N-terminus, compared to isoform a.
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G108062 人 TFEC (NM_001244583) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]