人 CBX2 (NM_032647) cDNA克隆

Accession: NM_032647
基因名称: CBX2
基因别名: M33; CDCA6; SRXY5
基因描述: Homo sapiens chromobox homolog 2 (CBX2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 636 (查看编码区序列)
翻译后氨基酸长度: 211 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks a 3' exon compared to variant 1, resulting in an alternate 3' coding region and UTR. It encodes a shorter isoform (2) with an unique C-terminus compared to isoform 1.
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G108195 人 CBX2 (NM_032647) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2010]