人 THAP1 (NM_199003) cDNA克隆

Accession: NM_199003
基因名称: THAP1
基因别名: DYT6
基因描述: Homo sapiens THAP domain containing, apoptosis associated protein 1 (THAP1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 162 (查看编码区序列)
翻译后氨基酸长度: 53 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks a coding exon compared to variant 1, which causes a frameshift. The resulting isoform (2) has a distinct and shorter C-terminus, as compared to isoform 1.
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G108220 人 THAP1 (NM_199003) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]