Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010]
人 FNTA (NM_002027) cDNA克隆
| Accession: | NM_002027 |
|---|---|
| 基因名称: | FNTA |
| 基因别名: | FPTA; PTAR2; PGGT1A |
| 基因描述: | Homo sapiens farnesyltransferase, CAAX box, alpha (FNTA), transcript variant 1, mRNA. |
| 种属: | Human |
| CDS区长度: | 1140 (查看编码区序列) |
| 翻译后氨基酸长度: | 379 (查看氨基酸序列) |
| Transcript Variant: | This variant (1) represents the longer transcript and encodes the functional protein. |
| 人 FNTA (NM_002027) cDNA克隆 | transcript variant 1 |
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