人 CTDSP1 (NM_182642) cDNA克隆

Accession: NM_182642
基因名称: CTDSP1
基因别名: NIF3; SCP1; NLIIF; NLI-IF
基因描述: Homo sapiens CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (CTDSP1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 783 (查看编码区序列)
翻译后氨基酸长度: 260 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
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G108762 人 CTDSP1 (NM_182642) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]