人 UNG (NM_003362) cDNA克隆

基本信息

Accession: NM_003362
基因名称: UNG
基因别名: DGU; UDG; UNG1; UNG2; HIGM4; HIGM5; UNG15
基因描述: Homo sapiens uracil-DNA glycosylase (UNG), transcript variant 1, mRNA.
种属: Human
CDS区长度: 915 (查看编码区序列)
翻译后氨基酸长度: 304 (查看氨基酸序列)
Transcript Variant: This variant (1) uses the downstream promoter and a full-length exon 1B. It encodes the UNG1 isoform, which includes a mitochondrial targeting sequence.

订购信息

产品编号 产品名称 载体 规格 价格
G109394 人 UNG (NM_003362) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 UNG (NM_003362) cDNA克隆 transcript variant 1
人 UNG (NM_080911) cDNA克隆 transcript variant 2

基因简介

This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010]

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