人 RNPS1 (NM_001286626) cDNA克隆

基本信息

Accession: NM_001286626
基因名称: RNPS1
基因别名: E5.1
基因描述: Homo sapiens RNA binding protein S1, serine-rich domain (RNPS1), transcript variant 4, mRNA.
种属: Human
CDS区长度: 849 (查看编码区序列)
翻译后氨基酸长度: 282 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks an alternate exon compared to variant 2. The resulting isoform (b) has a shorter and distinct N-terminus compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G109431 人 RNPS1 (NM_001286626) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RNPS1 (NM_006711) cDNA克隆 transcript variant 1
人 RNPS1 (NM_080594) cDNA克隆 transcript variant 2
人 RNPS1 (NM_001286625) cDNA克隆 transcript variant 3
人 RNPS1 (NM_001286626) cDNA克隆 transcript variant 4
人 RNPS1 (NM_001286627) cDNA克隆 transcript variant 5

基因简介

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

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