人 UPRT (NM_145052) cDNA克隆

Accession: NM_145052
基因名称: UPRT
基因别名: UPP; FUR1; RP11-311P8.3
基因描述: Homo sapiens uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) (UPRT), transcript variant 1, mRNA.
种属: Human
CDS区长度: 930 (查看编码区序列)
翻译后氨基酸长度: 309 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the functional protein.
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G109497 人 UPRT (NM_145052) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009]