人 FGL1 (NM_004467) cDNA克隆

Accession: NM_004467
基因名称: FGL1
基因别名: HFREP1; HP-041; LFIRE1; LFIRE-1
基因描述: Homo sapiens fibrinogen-like 1 (FGL1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 939 (查看编码区序列)
翻译后氨基酸长度: 312 (查看氨基酸序列)
Transcript Variant: This variant (1) appears to be the predominantly expressed transcript. It lacks an exon in the 5' UTR and has an alternate exon at the 5' end compared to the longest variant (4). All four variants encode the same protein.
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G109545 人 FGL1 (NM_004467) cDNA克隆 pDONR223 2ug质粒 点击询价

Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008]