人 AKR7A2 (NM_003689) cDNA克隆

Accession: NM_003689
基因名称: AKR7A2
基因别名: AFAR; AKR7; AFAR1; AFB1-AR1
基因描述: Homo sapiens aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (AKR7A2), mRNA.
种属: Human
CDS区长度: 1080 (查看编码区序列)
翻译后氨基酸长度: 359 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G109828 人 AKR7A2 (NM_003689) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. [provided by RefSeq, Oct 2011]