人 PPP1CA (NM_206873) cDNA克隆

Accession: NM_206873
基因名称: PPP1CA
基因别名: PP1A; PP-1A; PPP1A; PP1alpha
基因描述: Homo sapiens protein phosphatase 1, catalytic subunit, alpha isozyme (PPP1CA), transcript variant 2, mRNA.
种属: Human
CDS区长度: 861 (查看编码区序列)
翻译后氨基酸长度: 286 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1. The resulting isoform (2) lacks an internal region, as compared to isoform 1.
产品编号 产品名称 载体 规格 价格
G109842 人 PPP1CA (NM_206873) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]