人 ICA1 (NM_022307) cDNA克隆

Accession: NM_022307
基因名称: ICA1
基因别名: ICA69; ICAp69
基因描述: Homo sapiens islet cell autoantigen 1, 69kDa (ICA1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1452 (查看编码区序列)
翻译后氨基酸长度: 483 (查看氨基酸序列)
Transcript Variant: This variant (1, also referred to as IS10) has an alternate first exon and uses an alternate splice junction, both in the 5' UTR, compared to variant 3. Variants 1, 2, and 3 all encode the same isoform (a).
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G110014 人 ICA1 (NM_022307) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]