人 SH3GLB1 (NM_001206653) cDNA克隆

Accession: NM_001206653
基因名称: SH3GLB1
基因别名: Bif-1; CGI-61; PPP1R70; dJ612B15.2
基因描述: Homo sapiens SH3-domain GRB2-like endophilin B1 (SH3GLB1), transcript variant 4, mRNA.
种属: Human
CDS区长度: 798 (查看编码区序列)
翻译后氨基酸长度: 265 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks an exon in the 5' region, resulting in a downstream AUG start codon, compared to variant 1. The resulting isoform (4) has a shorter N-terminus, compared to isoform 1.
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G110293 人 SH3GLB1 (NM_001206653) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]