人 CABLES1 (NM_138375) cDNA克隆

基本信息

Accession: NM_138375
基因名称: CABLES1
基因别名: CABL1; IK3-1; CABLES; HsT2563
基因描述: Homo sapiens Cdk5 and Abl enzyme substrate 1 (CABLES1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1107 (查看编码区序列)
翻译后氨基酸长度: 368 (查看氨基酸序列)
Transcript Variant: This variant (1) uses an alternate first exon that contains the translation initiation site, resulting in an isoform (1) with a distinct N-terminus.

订购信息

产品编号 产品名称 载体 规格 价格
G110332 人 CABLES1 (NM_138375) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CABLES1 (NM_138375) cDNA克隆 transcript variant 1
人 CABLES1 (NM_001100619) cDNA克隆 transcript variant 2
人 CABLES1 (NM_001256438) cDNA克隆 transcript variant 4

基因简介

This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

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