人 ARFGAP1 (NM_018209) cDNA克隆

基本信息

Accession: NM_018209
基因名称: ARFGAP1
基因别名: ARF1GAP; HRIHFB2281
基因描述: Homo sapiens ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1221 (查看编码区序列)
翻译后氨基酸长度: 406 (查看氨基酸序列)
Transcript Variant: This variant (1) lacks an in-frame exon and uses an alternate in-frame splice site in the 3' coding region, compared to variant 2. The encoded isoform (a) is shorter, compared to isoform b.

订购信息

产品编号 产品名称 载体 规格 价格
G110805 人 ARFGAP1 (NM_018209) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ARFGAP1 (NM_018209) cDNA克隆 transcript variant 1
人 ARFGAP1 (NM_175609) cDNA克隆 transcript variant 2
人 ARFGAP1 (NM_001281482) cDNA克隆 transcript variant 3
人 ARFGAP1 (NM_001281483) cDNA克隆 transcript variant 4
人 ARFGAP1 (NM_001281484) cDNA克隆 transcript variant 5

基因简介

The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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