人 TNFRSF10B (NM_147187) cDNA克隆

基本信息

Accession: NM_147187
基因名称: TNFRSF10B
基因别名: DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5
基因描述: Homo sapiens tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1236 (查看编码区序列)
翻译后氨基酸长度: 411 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an in-frame coding segment compared to variant 1. The resulting isoform (2) lacks an internal region, as compared to isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G111058 人 TNFRSF10B (NM_147187) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TNFRSF10B (NM_003842) cDNA克隆 transcript variant 1
人 TNFRSF10B (NM_147187) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]

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