人 CRBN (NM_001173482) cDNA克隆

Accession: NM_001173482
基因名称: CRBN
基因别名: MRT2; MRT2A
基因描述: Homo sapiens cereblon (CRBN), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1326 (查看编码区序列)
翻译后氨基酸长度: 441 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1.
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G111078 人 CRBN (NM_001173482) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]