人 CFH (NM_000186) cDNA克隆

基本信息

Accession: NM_000186
基因名称: CFH
基因别名: FH; HF; HF1; HF2; HUS; FHL1; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3
基因描述: Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3696 (查看编码区序列)
翻译后氨基酸长度: 1231 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).

订购信息

产品编号 产品名称 载体 规格 价格
G111158 人 CFH (NM_000186) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CFH (NM_000186) cDNA克隆 transcript variant 1
人 CFH (NM_001014975) cDNA克隆 transcript variant 2

基因简介

This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011]

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