人 IL16 (NM_001172128) cDNA克隆

Accession: NM_001172128
基因名称: IL16
基因别名: LCF; NIL16; PRIL16; prIL-16
基因描述: Homo sapiens interleukin 16 (IL16), transcript variant 3, mRNA.
种属: Human
CDS区长度: 3996 (查看编码区序列)
翻译后氨基酸长度: 1331 (查看氨基酸序列)
Transcript Variant: This variant (3) has multiple differences and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) is longer, compared to isoform 1.
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G111223 人 IL16 (NM_001172128) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]