人 CHN1 (NM_001822) cDNA克隆

Accession: NM_001822
基因名称: CHN1
基因别名: NC; CHN; DURS2; ARHGAP2; RHOGAP2
基因描述: Homo sapiens chimerin 1 (CHN1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1380 (查看编码区序列)
翻译后氨基酸长度: 459 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (1, also known as alpha 2-chimerin).
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G111261 人 CHN1 (NM_001822) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]