人 CHRM1 (NM_000738) cDNA克隆

Accession: NM_000738
基因名称: CHRM1
基因别名: M1; HM1; M1R
基因描述: Homo sapiens cholinergic receptor, muscarinic 1 (CHRM1), mRNA.
种属: Human
CDS区长度: 1383 (查看编码区序列)
翻译后氨基酸长度: 460 (查看氨基酸序列)
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G111274 人 CHRM1 (NM_000738) cDNA克隆 pDONR223 2ug质粒 点击询价

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]