人 CHRM2 (NM_001006630) cDNA克隆

Accession: NM_001006630
基因名称: CHRM2
基因别名: HM2
基因描述: Homo sapiens cholinergic receptor, muscarinic 2 (CHRM2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1401 (查看编码区序列)
翻译后氨基酸长度: 466 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript. Variants 1 through 8 encode the same protein (isoform a).
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G123473 人 CHRM2 (NM_001006630) cDNA克隆 pDONR223 2ug质粒 点击询价

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]