人 NR1H2 (NM_007121) cDNA克隆

基本信息

Accession: NM_007121
基因名称: NR1H2
基因别名: NER; UNR; LXRB; LXR-b; NER-I; RIP15
基因描述: Homo sapiens nuclear receptor subfamily 1, group H, member 2 (NR1H2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1386 (查看编码区序列)
翻译后氨基酸长度: 461 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G111289 人 NR1H2 (NM_007121) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NR1H2 (NM_007121) cDNA克隆 transcript variant 1
人 NR1H2 (NM_001256647) cDNA克隆 transcript variant 2

基因简介

The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]

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