人 RARA (NM_001145301) cDNA克隆

Accession: NM_001145301
基因名称: RARA
基因别名: RAR; NR1B1
基因描述: Homo sapiens retinoic acid receptor, alpha (RARA), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1389 (查看编码区序列)
翻译后氨基酸长度: 462 (查看氨基酸序列)
Transcript Variant: This variant (3) reflects the use of an alternate promoter and contains a different 5' UTR segment, compared to variant 1. Variants 1 and 3 encode the same isoform (1).
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G111298 人 RARA (NM_001145301) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]