人 RXRG (NM_001256571) cDNA克隆

Accession: NM_001256571
基因名称: RXRG
基因别名: RXRC; NR2B3
基因描述: Homo sapiens retinoid X receptor, gamma (RXRG), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1023 (查看编码区序列)
翻译后氨基酸长度: 340 (查看氨基酸序列)
Transcript Variant: This variant (4) uses an alternate internal promoter, and it thus differs in the 5' UTR and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (c, also known as RXRgamma2) is shorter at the N-terminus, compared to isoform a. Both variants 3 and 4 encode isoform c.
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G111313 人 RXRG (NM_001256571) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]