人 NUF2 (NM_031423) cDNA克隆

Accession: NM_031423
基因名称: NUF2
基因别名: CDCA1; CT106; NUF2R
基因描述: Homo sapiens NUF2, NDC80 kinetochore complex component (NUF2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1395 (查看编码区序列)
翻译后氨基酸长度: 464 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
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G111328 人 NUF2 (NM_031423) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]