人 U2AF2 (NM_007279) cDNA克隆

Accession: NM_007279
基因名称: U2AF2
基因别名: U2AF65
基因描述: Homo sapiens U2 small nuclear RNA auxiliary factor 2 (U2AF2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1428 (查看编码区序列)
翻译后氨基酸长度: 475 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
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G111404 人 U2AF2 (NM_007279) cDNA克隆 pDONR223 2ug质粒 点击询价

U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date. [provided by RefSeq, Jul 2008]