人 WARS (NM_213646) cDNA克隆

Accession: NM_213646
基因名称: WARS
基因别名: IFI53; IFP53; GAMMA-2
基因描述: Homo sapiens tryptophanyl-tRNA synthetase (WARS), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1293 (查看编码区序列)
翻译后氨基酸长度: 430 (查看氨基酸序列)
Transcript Variant: This variant (4) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (b) uses a downstream start codon but has the same C-terminus compared to isoform a. Variants 3 and 4 both encode isoform b.
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G111408 人 WARS (NM_213646) cDNA克隆 pDONR223 2ug质粒 点击询价

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]