人 PPARG (NM_138712) cDNA克隆

Accession: NM_138712
基因名称: PPARG
基因别名: GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARgamma
基因描述: Homo sapiens peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1434 (查看编码区序列)
翻译后氨基酸长度: 477 (查看氨基酸序列)
Transcript Variant: This variant (1) differs in the 5' UTR and 5' coding region compared to variant 2. Variants 1, 3, and 4 encode the same isoform (1), which has a shorter, distinct N-terminus compared to isoform 2.
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G111467 人 PPARG (NM_138712) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]