人 ERLEC1 (NM_001127398) cDNA克隆

Accession: NM_001127398
基因名称: ERLEC1
基因别名: CIM; XTP3-B; C2orf30; CL24936; CL25084; XTP3TPB
基因描述: Homo sapiens endoplasmic reticulum lectin 1 (ERLEC1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1290 (查看编码区序列)
翻译后氨基酸长度: 429 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (3, also known as hXTP3-B-short) that is shorter than isoform 1.
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G111574 人 ERLEC1 (NM_001127398) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a resident endoplasmic reticulum (ER) protein that functions in N-glycan recognition. This protein is thought to be involved in ER-associated degradation via its interaction with the membrane-associated ubiquitin ligase complex. It also functions as a regulator of multiple cellular stress-response pathways in a manner that promotes metastatic cell survival. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 21. [provided by RefSeq, Aug 2011]