人 DPH2 (NM_001384) cDNA克隆

Accession: NM_001384
基因名称: DPH2
基因别名: DPH2L2
基因描述: Homo sapiens DPH2 homolog (S. cerevisiae) (DPH2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1470 (查看编码区序列)
翻译后氨基酸长度: 489 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
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G111642 人 DPH2 (NM_001384) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]