人 RABGEF1 (NM_001287062) cDNA克隆

基本信息

Accession: NM_001287062
基因名称: RABGEF1
基因别名: RAP1; RABEX5; rabex-5
基因描述: Homo sapiens RAB guanine nucleotide exchange factor (GEF) 1 (RABGEF1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1476 (查看编码区序列)
翻译后氨基酸长度: 491 (查看氨基酸序列)
Transcript Variant: This variant (3) contains alternate 5' exon structure and includes an additional internal exon, and it thus differs in its 5' UTR and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (c) is longer at the N-terminus, compared to isoform a. Both variants 3 and 4 encode isoform c.

订购信息

产品编号 产品名称 载体 规格 价格
G111665 人 RABGEF1 (NM_001287062) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RABGEF1 (NM_001287060) cDNA克隆 transcript variant 1
人 RABGEF1 (NM_001287061) cDNA克隆 transcript variant 2
人 RABGEF1 (NM_001287062) cDNA克隆 transcript variant 3
人 RABGEF1 (NM_014504) cDNA克隆 transcript variant 4

基因简介

RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).[supplied by OMIM, Mar 2010]

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