人 UGDH (NM_003359) cDNA克隆

基本信息

Accession: NM_003359
基因名称: UGDH
基因别名: GDH; UGD; UDPGDH; UDP-GlcDH
基因描述: Homo sapiens UDP-glucose 6-dehydrogenase (UGDH), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1485 (查看编码区序列)
翻译后氨基酸长度: 494 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G111695 人 UGDH (NM_003359) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 UGDH (NM_003359) cDNA克隆 transcript variant 1
人 UGDH (NM_001184700) cDNA克隆 transcript variant 2
人 UGDH (NM_001184701) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

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