人 ALDH1L1 (NM_001270364) cDNA克隆

Accession: NM_001270364
基因名称: ALDH1L1
基因别名: FDH; FTHFD; 10-fTHF; 10-FTHFDH
基因描述: Homo sapiens aldehyde dehydrogenase 1 family, member L1 (ALDH1L1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2739 (查看编码区序列)
翻译后氨基酸长度: 912 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest protein (isoform 1).
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G111833 人 ALDH1L1 (NM_001270364) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]