人 HCK (NM_001172129) cDNA克隆

基本信息

Accession: NM_001172129
基因名称: HCK
基因别名: JTK9; p59Hck; p61Hck
基因描述: Homo sapiens hemopoietic cell kinase (HCK), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1518 (查看编码区序列)
翻译后氨基酸长度: 505 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes two isoforms due to the use of alternative translation initiation codons, as demonstrated in PMIDs 1875927 and 7791757. The longer isoform (a, also known as p61HCK) is derived from an upstream non-AUG (CUG) start codon, while the shorter isoform (b, also known as p59HCK) is derived from a downstream AUG start codon. The shorter isoform (b) is represented in this RefSeq. Both variants 1 and 4 encode isoform b.

订购信息

产品编号 产品名称 载体 规格 价格
G111845 人 HCK (NM_001172129) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 HCK (NM_001172129) cDNA克隆 transcript variant 1
人 HCK (NM_002110) cDNA克隆 transcript variant 1
人 HCK (NM_001172130) cDNA克隆 transcript variant 2
人 HCK (NM_001172131) cDNA克隆 transcript variant 2
人 HCK (NM_001172132) cDNA克隆 transcript variant 3
人 HCK (NM_001172133) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010]

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