人 PRAME (NM_006115) cDNA克隆

基本信息

Accession: NM_006115
基因名称: PRAME
基因别名: MAPE; OIP4; CT130; OIP-4
基因描述: Homo sapiens preferentially expressed antigen in melanoma (PRAME), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1530 (查看编码区序列)
翻译后氨基酸长度: 509 (查看氨基酸序列)
Transcript Variant: This variant (1) lacks a segment in the 5' UTR compared to the longest variant (2). Both variants encode the same protein.

订购信息

产品编号 产品名称 载体 规格 价格
G111900 人 PRAME (NM_006115) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PRAME (NM_006115) cDNA克隆 transcript variant 1
人 PRAME (NM_206953) cDNA克隆 transcript variant 2
人 PRAME (NM_206954) cDNA克隆 transcript variant 3
人 PRAME (NM_206955) cDNA克隆 transcript variant 4
人 PRAME (NM_206956) cDNA克隆 transcript variant 5

基因简介

This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]

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