人 MSL3 (NM_001282174) cDNA克隆

基本信息

Accession: NM_001282174
基因名称: MSL3
基因别名: MSL3L1
基因描述: Homo sapiens male-specific lethal 3 homolog (Drosophila) (MSL3), transcript variant 6, mRNA.
种属: Human
CDS区长度: 1119 (查看编码区序列)
翻译后氨基酸长度: 372 (查看氨基酸序列)
Transcript Variant: This variant (6) differs in its 5' UTR and 5' coding region, and uses a distinct start codon, compared to variant 1. The resulting isoform (f) has a distinct N-terminus and is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G111987 人 MSL3 (NM_001282174) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MSL3 (NM_078629) cDNA克隆 transcript variant 1
人 MSL3 (NM_006800) cDNA克隆 transcript variant 3
人 MSL3 (NM_078628) cDNA克隆 transcript variant 4
人 MSL3 (NM_001193270) cDNA克隆 transcript variant 5
人 MSL3 (NM_001282174) cDNA克隆 transcript variant 6

基因简介

This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]

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