人 CALD1 (NM_033139) cDNA克隆

基本信息

Accession: NM_033139
基因名称: CALD1
基因别名: CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22
基因描述: Homo sapiens caldesmon 1 (CALD1), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1677 (查看编码区序列)
翻译后氨基酸长度: 558 (查看氨基酸序列)
Transcript Variant: This variant (4) differs in the 5' UTR and 5' coding region, and uses an alternate in-frame splice site in the central coding region, compared to variant 1. It is mainly expressed in non-muscle tissues or cells. The resulting isoform (4, also known as HeLa l-CaD I) contains a distinct N-terminus and is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G112121 人 CALD1 (NM_033139) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CALD1 (NM_033138) cDNA克隆 transcript variant 1
人 CALD1 (NM_004342) cDNA克隆 transcript variant 2
人 CALD1 (NM_033157) cDNA克隆 transcript variant 3
人 CALD1 (NM_033139) cDNA克隆 transcript variant 4
人 CALD1 (NM_033140) cDNA克隆 transcript variant 5

基因简介

This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

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