人 ZBTB7B (NM_001252406) cDNA克隆

Accession: NM_001252406
基因名称: ZBTB7B
基因别名: THPOK; ZFP67; ZBTB15; ZFP-67; c-KROX; hcKROX; ZNF857B
基因描述: Homo sapiens zinc finger and BTB domain containing 7B (ZBTB7B), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1722 (查看编码区序列)
翻译后氨基酸长度: 573 (查看氨基酸序列)
Transcript Variant: This variant (3) represents the longest transcript and encodes the longer isoform (2).
产品编号 产品名称 载体 规格 价格
G112153 人 ZBTB7B (NM_001252406) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]