人 NET1 (NM_005863) cDNA克隆

Accession: NM_005863
基因名称: NET1
基因别名: NET1A; ARHGEF8
基因描述: Homo sapiens neuroepithelial cell transforming 1 (NET1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1629 (查看编码区序列)
翻译后氨基酸长度: 542 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
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G112162 人 NET1 (NM_005863) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]