人 EME1 (NM_001166131) cDNA克隆

Accession: NM_001166131
基因名称: EME1
基因别名: MMS4L; SLX2A
基因描述: Homo sapiens essential meiotic structure-specific endonuclease 1 (EME1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1752 (查看编码区序列)
翻译后氨基酸长度: 583 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
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G112350 人 EME1 (NM_001166131) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]