人 P2RX7 (NM_002562) cDNA克隆

Accession: NM_002562
基因名称: P2RX7
基因别名: P2X7
基因描述: Homo sapiens purinergic receptor P2X, ligand-gated ion channel, 7 (P2RX7), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1788 (查看编码区序列)
翻译后氨基酸长度: 595 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes a functional protein.
产品编号 产品名称 载体 规格 价格
G112410 人 P2RX7 (NM_002562) cDNA克隆 pDONR223 2ug质粒 点击询价

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]