人 TNIP1 (NM_001258456) cDNA克隆

Accession: NM_001258456
基因名称: TNIP1
基因别名: VAN; NAF1; ABIN-1; nip40-1
基因描述: Homo sapiens TNFAIP3 interacting protein 1 (TNIP1), transcript variant 10, mRNA.
种属: Human
CDS区长度: 1671 (查看编码区序列)
翻译后氨基酸长度: 556 (查看氨基酸序列)
Transcript Variant: This variant (10) lacks two exons in the 3' coding region which results in a frameshift compared to variant 1. The resulting protein (isoform 6) is shorter and has a distinct C-terminus compared to isoform 1.
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G112525 人 TNIP1 (NM_001258456) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]