人 MX1 (NM_001282920) cDNA克隆

Accession: NM_001282920
基因名称: MX1
基因别名: MX; MxA; IFI78; IFI-78K
基因描述: Homo sapiens myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) (MX1), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1527 (查看编码区序列)
翻译后氨基酸长度: 508 (查看氨基酸序列)
Transcript Variant: This variant (4) differs in the 5' UTR and lacks three exons in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (b, also known as varMxA) is shorter and has a distinct C-terminus, compared to isoform a. This variant is supported by data in PMID: 20603636.
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G112569 人 MX1 (NM_001282920) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]