人 ATRIP (NM_032166) cDNA克隆

Accession: NM_032166
基因名称: ATRIP
基因描述: Homo sapiens ATR interacting protein (ATRIP), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2295 (查看编码区序列)
翻译后氨基酸长度: 764 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
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G112682 人 ATRIP (NM_032166) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012]