人 ANAPC10 (NM_001256711) cDNA克隆

基本信息

Accession: NM_001256711
基因名称: ANAPC10
基因别名: DOC1; APC10
基因描述: Homo sapiens anaphase promoting complex subunit 10 (ANAPC10), transcript variant 7, mRNA.
种属: Human
CDS区长度: 345 (查看编码区序列)
翻译后氨基酸长度: 114 (查看氨基酸序列)
Transcript Variant: This variant (7) differs in the 5' UTR and includes an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. Variants 6 and 7 encode the same isoform (3), which is shorter and has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G113208 人 ANAPC10 (NM_001256711) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ANAPC10 (NM_001256706) cDNA克隆 transcript variant 1
人 ANAPC10 (NM_014885) cDNA克隆 transcript variant 2
人 ANAPC10 (NM_001256707) cDNA克隆 transcript variant 3
人 ANAPC10 (NM_001256708) cDNA克隆 transcript variant 4
人 ANAPC10 (NM_001256709) cDNA克隆 transcript variant 5
人 ANAPC10 (NM_001256710) cDNA克隆 transcript variant 6
人 ANAPC10 (NM_001256711) cDNA克隆 transcript variant 7
人 ANAPC10 (NM_001256712) cDNA克隆 transcript variant 8

基因简介

ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).[supplied by OMIM, Feb 2011]

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