人 RCAN1 (NM_004414) cDNA克隆

基本信息

Accession: NM_004414
基因名称: RCAN1
基因别名: CSP1; DSC1; RCN1; DSCR1; MCIP1; ADAPT78
基因描述: Homo sapiens regulator of calcineurin 1 (RCAN1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 759 (查看编码区序列)
翻译后氨基酸长度: 252 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).

订购信息

产品编号 产品名称 载体 规格 价格
G113305 人 RCAN1 (NM_004414) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RCAN1 (NM_004414) cDNA克隆 transcript variant 1
人 RCAN1 (NM_203417) cDNA克隆 transcript variant 2
人 RCAN1 (NM_203418) cDNA克隆 transcript variant 3
人 RCAN1 (NM_001285389) cDNA克隆 transcript variant 4
人 RCAN1 (NM_001285391) cDNA克隆 transcript variant 5
人 RCAN1 (NM_001285392) cDNA克隆 transcript variant 6
人 RCAN1 (NM_001285393) cDNA克隆 transcript variant 7

基因简介

The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

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