人 STIP1 (NM_006819) cDNA克隆

基本信息

Accession: NM_006819
基因名称: STIP1
基因别名: HOP; P60; STI1; STI1L; IEF-SSP-3521
基因描述: Homo sapiens stress-induced-phosphoprotein 1 (STIP1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1632 (查看编码区序列)
翻译后氨基酸长度: 543 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (b) has a distinct N-terminus and is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G113431 人 STIP1 (NM_006819) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 STIP1 (NM_001282652) cDNA克隆 transcript variant 1
人 STIP1 (NM_001282653) cDNA克隆 transcript variant 3
人 STIP1 (NM_006819) cDNA克隆 transcript variant 2

基因简介

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]

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