人 DTNB (NM_021907) cDNA克隆

Accession: NM_021907
基因名称: DTNB
基因描述: Homo sapiens dystrobrevin, beta (DTNB), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1884 (查看编码区序列)
翻译后氨基酸长度: 627 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript, and encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G113626 人 DTNB (NM_021907) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]