人 APPBP2 (NM_006380) cDNA克隆

Accession: NM_006380
基因名称: APPBP2
基因别名: PAT1; APP-BP2; HS.84084
基因描述: Homo sapiens amyloid beta precursor protein (cytoplasmic tail) binding protein 2 (APPBP2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1758 (查看编码区序列)
翻译后氨基酸长度: 585 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and the longer isoform (1).
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G113725 人 APPBP2 (NM_006380) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]